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Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation?

Sarah L Booth
DOI: http://dx.doi.org/10.1111/j.1753-4887.2010.00274.x 178-181 First published online: 1 March 2010


Numerous risk factors for instability of oral anticoagulation have been identified, including variability in vitamin K intake. However, few studies have directly tested the feasibility of manipulating dietary vitamin K to achieve stable oral anticoagulation. Recent findings from a randomized clinical trial suggest that dietary vitamin K manipulation is a viable option for managing stability of oral anticoagulant therapy. The approach appears to be effective for those patients who are under-anticoagulated and consume a small number of vitamin K-rich food sources. While an encouraging option for management of warfarin therapy, longer-term studies in different patient populations are required.

  • anticoagulants
  • diet
  • phylloquinone
  • vitamin K
  • warfarin
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