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Is Black Cohosh Estrogenic?

DOI: http://dx.doi.org/10.1301/nr.2003.may.183-186 183-186 First published online: 1 May 2003


Many women seek safe and effective alternative therapies for the treatment of menopausal symptoms. Black cohosh, a botanical product, is one such treatment. Its mechanism of action may involve estrogenic effects, but new data dispute the estrogenic theory and indicate that extracts of black cohosh do not bind to the estrogen receptor, up-regulate estrogen-dependent genes, or stimulate the growth of estrogen-dependent tumors in animal models.

  • black cohosh
  • botanical
  • estrogenic
  • menopause

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