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Omega-3 Fatty Acids Alter Soluble Coronary Heart Disease Patients Markers of Endothelial Function in

Mohsen Meydani D.V.M., Ph D
DOI: http://dx.doi.org/10.1111/j.1753-4887.2000.tb07812.x 56-59 First published online: 1 February 2000


Several studies have indicated that omega-3 polyunsaturated fatty acids in fish oil have protective effects on cardiovascular disease by reducing vascular endothelial inflammation in atherosclerosis. In a recent study, supplementation of patients with fish oil following coronary angioplasty elevated levels of lipid peroxides and two adhesion molecules in plasma suggesting a proinflammatory action of fish oil. However, decreases in several plasma markers of endothelial hemostatic activity indicated a healthier and better vasculature associated with fish oil supplementation.

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